Like magnesium citrate, other magnesium supplements including magnesium oxide, chloride, gluconate and carbonate also result in diarrhea. As a result, the patient suffers from malabsorption, which defeats the point of a multivitamin. This is due to too many unabsorbed magnesium ions in the gut which draw out water into the intestines, and also causes bowel over-stimulation. Unsurprisingly, most magnesium citrate supplements result in diarrhea вЂ“ a major cause of dehydration and electrolyte loss. For example, the cheapest salt, magnesium citrate, is used clinically as a laxative for bowel preparation before colorectal surgery. Different magnesium salts vary hugely in their affect on your body. However, magnesium is not available in pure elemental form, and is only provided in various salt forms.

To avoid deficiency, supplementing with magnesium is recommended. This is especially common in people who have high protein, calcium, or vitamin D intake as they increase your need for magnesium due to intracellular competition between ions in the intestine вЂ“ a key process in homeostasis. Severe magnesium deficiency can also result in other ion deficiencies which are incredibly harmful for your body. These vary along the spectrum, starting from appetite loss and nausea, and worsen to cramps, seizures and coronary spasms. The plethora of roles filled by magnesium means that magnesium deficiency can result in severe health conditions. In addition, magnesium promotes a strong immune system. Outside the brain, magnesium is utilized for many other biochemical reactions including (but not limited to) bone and muscle function, blood clotting and insulin secretion. In the last decade, scientists have found that increasing intracellular Mg2+ promotes structural synapse density, plasticity, and also increases the number of presynaptic terminals. This is especially the case in hippocampal neurons which control memory. Magnesium, a divalent cation, is important for neuronal activity as it is a cofactor for neural receptors in the brain. Supplementing with magnesium threonate is specifically used for normalising intracellular magnesium levels in the brain, though other benefits also occur. Magnesium L-threonate is the magnesium salt of the naturally occurring vitamin C metabolite, threonic acid. Why Magnesium Is Important вЂ“ But Most Magnesium Supplements Are Terrible This article will explain why magnesium threonate is the best magnesium supplement on the market for targeting the brain and realizing the neurological benefits of magnesium supplementation. Further, magnesium L-threonate doesnвЂ™t have the digestive side effects which are problematic in other magnesium supplements. Unlike other magnesium supplements, magnesium L-threonate can easily cross the blood-brain barrier as such, it is considered a nootropic. Magnesium L-threonate, also known as magnesium threonate, is one of the least well-known forms of magnesium, and yet it may actually be the best.

Best form of magnesium for depression